CTC ADN - Medications in Obstetrics for Nursing Students

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Effects on Mom/Baby
Antepartum Electrolyte replacement Antidote for hypermagnesium
Usual dose: 1g IV over 3-5 mins

Antepartum Betamethosone Steriod Lung maturity Increase fetal lung maturity
12.5mg IM q 24 hrs x 2 doses. Given to mom when PTL (24 - 34 wks)

Antepartum Prostin E2 Prostaglandin Termination of pregnancy n/v/d, fever
May be premedicated with Tylenol, antidiarrheal and antiemetic

Antepartum Apresoline Antihypertensive BP control
Given IVP for acute hypertension.

Antepartum Ativan CNS Agent Anticonvulsant Tx
Used during seizure. Must be kept refrigerated.

Antepartum Anticonvulsant Anticonvulsant Tx; Tx of PTL During loading dose: Facial flushing, warmth. During tx: hypermagnesium (loss of reflexes, resp arrest, cardiac arrest)
First choice during seizure and anti-seizure; Also used for PTL. DTRs 1st sign of hypermagnesia; Therapeutic level 4-8 mg/dl. Given thru infusion pump

Antepartum Aldomet Antihypertensive BP control
DOC for antihypertension maintenance

Antepartum Procardia Calcium-channel blocker Tocolytis; BP Control Hypotension, tachycardia, facial flushing, h/a
Off-label use for tocolysis. Co-administration with Ritodrine or Terbutaline OK. Do not give with MgSO4. Check BP prior to administering

Antepartum Yutopar Tocolytic Tocolysis Hypotension, tachycardia, palpitations, pulmonary edema, facial flushing. Fetal tachycardia.
Given IV thru infusion pump titration first. Then moved to PO. Not used much anymore.

Antepartum Brethine Tocolytic Tocolysis Hypotension, tachycardia, palpitations, pulmonary edema, facial flushing. Fetal tachycardia.
Given IV thru infusion pump titration. Then moved to PO. May use SQ doses for acute, short-term use. Used 2nd most after MgSO4

Intrapartum Marcaine Local anesthetic Epidural anesthesia Complications r/t hypotension episode with epidural
Most have BP monitored frequently (q 15 mins) with epidural anesthesia.

Intrapartum Duramorph Morphine Narcotic analgesic Pain relief (surgical) Sedation
Duramorph placed in epiddural line for continued pain relief up to 24 hrs. Morphine usual drug in PCA. Also given in RR for pain relief.

Intrapartum Anaprox NSAID Pain relief

Intrapartum Percocet Combination analgesic Pain relief Sedation

Intrapartum Rhogam Immunoglobulin Prevention of development of antibodies to fetus's Rh-positive blood
Given antepartum to mom who is Rh negative: at 28 wks and after amnio or abortion; and to Rh negative mom at delivery who's baby is Rh positive.

Newborn Survanta Lung surfactant Improve lung surfactant to decrease incidence of RDS
Given intratracheal only within 15 mins of birth; rescue given within 8 hrs of age. Indicated for infants 600-1750g

Newborn Stadol Narcotic analgesic Pain relief Sedation. Can cause transient loss of FHR variability. Neonatal resp if given close to delivery

Newborn Antibiotic Prevention of neonatorum ophthalmia
Prevention blindness from gonorrhea, Chlamydia. Should be given within first hr of life. State Law

Newborn Sublimaze Narcotic analgesic Synergistic effect with epidural Not absorbed systemically. Adverse effects r/t hypotension w/epidural
Small amts added to epidural anesthesia.

Newborn Recombivax HB Vaccine Prevention of HepB
Recommended within 1st 12 hrs after birth. Series of vaccines.

Newborn Demerol Narcotic Analgesic Pain relief Sedation. Can cause transient loss of FHR variability. Neonatal resp if given close to delivery

Newborn Cytotec Prostaglandin Cervical ripening Can cause uterine hyperstimulation
Approved as antiulcer. Off-label use in OB. Also used as abortifacient in 2nd trimester.

Newborn Nubain Narcotic Analgesic Pain relief Sedation. Can cause transient loss of FHR variability. Neonatal resp if given close to delivery

Newborn Narcan Narcotic antagonist Reversal of resp depression r/t narcotics
Given IM. Must assure neonatal dosage.

Newborn Pitocin Oxytoxic Labor induction; Prevention of PPH R/T hyperstimulation
Given IV thru infustion pump titration. 1st line of drug for prevention t/x of PPH

Newborn Aqua Mephyton Vitamin K Prevention of hemorrhagic dx of the newborn
Given IM within 1st hr of life.

Newborn Phenergan Antiemetic Prevention/tx of n/v Synergistic with narcotics Can cause extrapyramidal effects. Use lowest dose

Newborn Local anesthetic Episotomy
w/o epinephrine

Postpartum Hemabate Prostaglandin Severe PPH
3rd line of drug for PPH

Postpartum Colace Stool softner Prevention of constipation

Postpartum Feosol Iron replacement Prevention/tx of anemia May turn stools dark.
Take with Vit C to increase absorption

Postpartum Motrin NSAID Pain relief

Postpartum Depoprovera Progestin Birth Control
Given q 3 months IM

Postpartum Rubella vaccine Vaccine Prevention of rubella
Give PP only.

Postpartum Methergine Oxytocic PPH May increase BP
2nd line of drug for PPH (IV). Can be continued PO.